| 产品详情 |
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| Antigenic Specificity | CD104 (Integrin beta 4) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | lyophilized |
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| Applications | Western Blot: 0.5 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD104 (Integrin beta 4) Polyclonal Antibody. ITGB4 (Integrin, beta-4), also known as CD104 (Cluster of Differentiation 104), is a human gene. The gene encodes the integrin beta 4 subunits, a receptor for the laminins. This subunit tends to associate with alpha 6 subunits and is likely to play a pivotal role in the biology of invasive carcinoma. The ITGB4 gene is mapped on 17q25.1. Using expression profiling, Yang et al. found that ITGB4 was upregulated 6-fold by ZKSCAN3 in transfected human colon cancer cells compared with parental cells. They confirmed that ZKSCAN3 bound the promoter of ITGB4 in vitro and in vivo. ITGB4 knockdown by short hairpin RNA countered ZKSCAN3-augmented anchorage-independent colony formation in the colon cancer cel |
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| Immunogen | n/a |
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| Other Names | Integrin beta-4, GP150, CD104, ITGB4 |
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| Gene, Accession # | Entrez: 192897, 25724, 3691; Uniprot: A2A863, P16144, Q64632 |
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| Catalog # | PA5-79540 |
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| Price | |
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| Order / More Info | CD104 (Integrin beta 4) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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