产品详情 |
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Antigenic Specificity | NAPSA |
Clone | OTI1B5 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:400, Western Blot: 1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NAPSA Monoclonal Antibody (OTI1B5). Napsin 1 is an aspartic protease that is generally expressed in the lung, but also present in kidney and in metastatic carcinomas throughout the body. Napsin 1 processes surfactant protein B in healthy pulmonary and renal tissues, but is abnormally regulated when carcinogenesis occurs. Thus, many researchers have found napsin evaluation to be useful in identifying several cancers, and differentiating primary tumors from metastases. When combined with thyroid transcription factor analysis, napsin can be used as a specific biomarker for differentiation of carcinoma types. Napsin has also been associated with pulmonary alveolar proteinosis as well as in protein catabolism in renal tubules. |
Immunogen | n/a |
Other Names | KAP, Kdap, NAP1, NAPA, SNAPA, ASP4, TA01/TA02, asp 4, aspartyl protease 4, kidney-derived aspartic protease-like protein, napsin-1, napsin-A, pronapsin A |
Gene, Accession # | Entrez: 9476; Uniprot: O96009 |
Catalog # | MA5-27023 |
Price | |
Order / More Info | NAPSA Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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