Edit |   |
Antigenic Specificity | NARF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Western Blot: 1:250 - 1:500 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NARF Polyclonal Antibody. Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail do |
Immunogen | n/a |
Other Names | IOP2; iron-only hydrogenase-like protein 2; prenyl-dependent prelamin A binding protein |
Gene, Accession # | Entrez: 26502; Uniprot: Q9UHQ1 |
Catalog # | PA5-65754 |
Price | |
Order / More Info | NARF Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |