产品详情 |
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Antigenic Specificity | NARF |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NARF Polyclonal Antibody. Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. The protein encoded by this gene binds to the prenylated prelamin A carboxyl-terminal tail do |
Immunogen | n/a |
Other Names | IOP2, iron-only hydrogenase-like protein 2, prenyl-dependent prelamin A binding protein |
Gene, Accession # | Entrez: 26502, 67608; Uniprot: Q9CYQ7, Q9UHQ1 |
Catalog # | PA5-30516 |
Price | |
Order / More Info | NARF Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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