产品详情 |
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Antigenic Specificity | RRM1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | zebrafish |
Isotype | n/a |
Format | purified |
Size | 400 µl |
Concentration | n/a |
Applications | Western Blot: 1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RRM1 Polyclonal Antibody. This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. |
Immunogen | n/a |
Other Names | ribonucleoside-diphosphate reductase large subunit; ribonucleoside-diphosphate reductase subunit M1; ribonucleotide reductase M1 polypeptide; ribonucleotide reductase large subunit; ribonucleotide reductase; R1 subunit; ribonucleotide reductase; large subunit |
Gene, Accession # | Entrez: 30740; Uniprot: P79732 |
Catalog # | PA5-72674 |
Price | |
Order / More Info | RRM1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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