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| Antigenic Specificity | HPV Type 16 E7 |
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| Clone | 8C9 |
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| Host Species | Mouse |
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| Reactive Species | n/a |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | lyophilized |
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| Applications | Immunohistochemistry (Paraffin): 1:2, Immunoprecipitation: 1:10, Western Blot: 1:100 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | HPV Type 16 E7 Monoclonal Antibody (8C9). The HPV E7 proteins are small (HPV16 E7 comprising 98 amino acids, 15kDa), zinc binding phosphoproteins which are localised in the nucleus. They are structurally and functionally similar to the E1A protein of subgenus C adenoviruses. The first 16 amino-terminal amino acids of HPV16 E7 contain a region homologous to a segment of the conserved region 1 (CR1) of the E1A protein of subgenus C adenoviruses. The next domain, up to amino acid 37, is homologous to the entire region 2 (CR2) of E1A. Genetic studies have established that these domains are required for cell transformation in vitro, suggesting similarities in the mechanism of transformation by these viruses. The CR2 homology region contains the |
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| Immunogen | n/a |
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| Other Names | HPV16E7; HPV 16-E7 |
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| Gene, Accession # | n/a |
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| Catalog # | 28-0006 |
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| Price | |
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| Order / More Info | HPV Type 16 E7 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 11373270, 11439326, 12372298, 12556559, 16166303, 16945398, 20050971, 21697473, 21738683, 22457518, 22700466, 23152514, 24141769, 24798431, 26168014, 27065324 |
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