| 产品详情 |
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| Antigenic Specificity | H-Ras |
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| Clone | Y13-259 |
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| Host Species | Rat |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1, kappa |
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| Format | purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Immunofluorescence: Assay Dependent, Immunohistochemistry: Assay Dependent, Immunoprecipitation: Assay Dependent, Western Blot: Assay Dependent |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | H-Ras Monoclonal Antibody (Y13-259). HRAS belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. These proteins function in signal transduction pathways. They can bind GTP and GDP, and they have intrinsic GTPase activity. HRAS undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnorma |
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| Immunogen | n/a |
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| Other Names | Ha-Ras, Harvey-ras, Hras, H-Ras-1, Transforming protein p21, c-H-ras, p21ras, Ras, GTPase Hras, Hras1 |
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| Gene, Accession # | Entrez: 15461, 293621, 3265; Uniprot: P01112, P20171, Q61411 |
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| Catalog # | 33-7200 |
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| Price | |
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| Order / More Info | H-Ras Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10666033, 12527912, 16027734, 27793041 |
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