| 产品详情 |
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| Antigenic Specificity | PNP |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-10 µg/mg lysate, Western Blot: 1:2,000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PNP Polyclonal Antibody. This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. |
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| Immunogen | n/a |
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| Other Names | NP, PRO1837, PUNP, inosine phosphorylase, purine-nucleoside:orthophosphate ribosyltransferase |
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| Gene, Accession # | Entrez: 4860; Uniprot: P00491 |
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| Catalog # | A304-240A |
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| Price | |
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| Order / More Info | PNP Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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