| 产品详情 |
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| Antigenic Specificity | CHCHD6 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 µg/mL, Immunofluorescence: 1-4 µg/mL, Immunohistochemistry: 1:50-1:200, Western Blot: 0.4 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CHCHD6 Polyclonal Antibody. CHCHD6 is a member of a family of proteins containing a conserved (coiled coil 1)-(helix 1)-(coiled coil 2)-(helix 2) domain and has been observed in a complex with the mitochondrial proteins mitofilin, SAM50, metaxins 1 and 2, and CHCHD3. CHCHD6 knockdown causes severe defects in mitochondrial cristae morphology as well as reductions in cell growth, ATP production and oxygen consumption. This decrease of CHCHD6 also led to a reduction in mitofilin protein levels, while a knockdown of mitofilin resulted in a reduced level of CHCHD6, suggesting coordinate regulation between these two proteins. CHCHD6 knockdown in human cancer cells enhances their sensitivity to genotoxic anticancer drugs, suggesting that CHCHD6 ma |
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| Immunogen | n/a |
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| Other Names | CHCHD6, Coiled-coil-helix-coiled-coil-helix domain-containing protein 6, coiled coil helix cristae morphology 1, CHCM1, PPP1R23 |
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| Gene, Accession # | Entrez: 84303; Uniprot: Q9BRQ6 |
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| Catalog # | PA5-61567 |
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| Price | |
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| Order / More Info | CHCHD6 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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