产品详情 |
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Antigenic Specificity | CHD3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Immunocytochemistry: 1:100-1:1000, Immunofluorescence: 1:100-1:1000, Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CHD3 Polyclonal Antibody. CHD3 encodes a member of the CHD family of proteins which are characterized by the presence of chromo domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. |
Immunogen | n/a |
Other Names | chromodomain helicase DNA binding protein 3, ZFH, Mi2-ALPHA, Mi-2a |
Gene, Accession # | Entrez: 1107, 216848; Uniprot: Q12873 |
Catalog # | PA5-77916 |
Price | |
Order / More Info | CHD3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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