产品详情 |
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Antigenic Specificity | CHD5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry: 1:500-1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CHD5 Polyclonal Antibody. Chromodomain helicase DNA binding protein 5, also known as CHD5, is a member of the SNF2/RAD54 helicase family of chromatin remodeling and DNA-binding proteins (CDH proteins). Heavily expressed in both fetal and adult brain, CHD5 plays a role in nervous system development and acts as a tumor suppressor via the Arf/p53 pathway. CHD5, along with other chromo-domain proteins, forms remodeling complexes, such as NuRD, that promote normal neuroblast maturation and are thought to prevent overexpression of neuronal cells. Errors in these chromatin remodeling complexes can leave the cell in a perpetual state of growth, preventing differentiation and leading to tumor formation. Due to the importance of the CHD proteins in p |
Immunogen | n/a |
Other Names | Chromodomain-helicase-DNA-binding protein 5, CHD-5, ATP-dependent helicase CHD5, KIAA0444 |
Gene, Accession # | Entrez: 26038; Uniprot: Q8TDI0 |
Catalog # | PA5-63133 |
Price | |
Order / More Info | CHD5 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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