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| Product Name | GSK-484 hydrochloride |
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| Description | Purity >98%. GSK-484 is a potent and reversible inhibitor of PAD4 (Protein Arginine Deiminase 4) (IC50 = 50 nM) that binds to the low-calcium form of the enzyme. It is selective for PAD4 over PAD1-3. GSK-484 blocks the citrullination of PAD4 target proteins in human neutrophils and inhibits the formation of neutrophil extracellular traps in both mouse and human neutrophils. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | ((3S,4R)-3-Amino-4-hydroxypiperidin-1-yl)(2-(1-(cyclopropylmethyl)-1H-indol-2-yl)-7-methoxy-1-methyl-1H-benzo[d]imidazol-5-yl)methanone hydrochloride |
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| Gene, Accession, CAS # | CAS: 1652591-81-5 |
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| Catalog # | LS-H3745 |
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| Order / More Info | GSK-484 hydrochloride from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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