| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | CNTNAP1 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | mouse, rat |
|---|
| Isotype | n/a |
|---|
| Format | purified |
|---|
| Size | 100 µL |
|---|
| Concentration | n/a |
|---|
| Applications | Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000 |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | CNTNAP1 Polyclonal Antibody. Seems to play a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Seems to demarcate the paranodal region of the axo-glial junction. In association with contactin may have a role in the signaling between axons and myelinating glial cells. Mice that lack CNTAP1 exhibit tremor, ataxia, and significant motor paresis. Normal paranodal junctions fail to form, and the organization of the paranodal loops is disrupted. Contactin is undetectable in the paranodes, and potassium channels are displaced from the juxtaparanodal into the paranodal domains. Also results in a severe decrease in peripheral nerve conduction velocity. |
|---|
| Immunogen | n/a |
|---|
| Other Names | AI841080, Caspr1, Cntnap1, NCP1, Nrxn4, contactin associated protein-like 1, p190, shm |
|---|
| Gene, Accession # | Entrez: 53321, 84008; Uniprot: O54991, P97846 |
|---|
| Catalog # | PA5-78502 |
|---|
| Price | |
|---|
| Order / More Info | CNTNAP1 Antibody from INVITROGEN ANTIBODIES |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|