| 产品详情 |
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| Antigenic Specificity | IL-1 alpha |
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| Clone | 40508 |
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| Host Species | Rat |
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| Reactive Species | mouse |
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| Isotype | IgG2B |
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| Format | purified |
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| Size | 500 µg |
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| Concentration | lyophilized |
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| Applications | ELISA: 0.1-0.4 µg/mL (Detection), 2-8 µg/mL (Capture), Neutralization: 0.2-0.6 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | IL-1 alpha Monoclonal Antibody (40508). IL-1 alpha (Interleukin-1 alpha) is a proinflammatory cytokine expressed by monocytes, macrophages, and dendritic cells. IL-1 alpha is coded by the IL1A gene and signals through two receptors, IL-1RI and IL-1RII, both of which are shared with IL-1 beta. IL1A is located on the q arm on chromosome 2 at position 13. IL-1 alpha plays an important role in innate host defense by triggering the production of other proinflammatory cytokines in target cells and initiating acute-phase responses. IL-1 alpha activity can be moderated by IL-1 Receptor Antagonist (IL-1RA), a protein produced by many cell types that blocks receptor binding through competitive inhibition. IL-1 alpha is a pleiotropic cytokine involved |
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| Immunogen | n/a |
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| Other Names | IL-1 alpha, hematopoietin-1, interleukin-1 alpha, preinterleukin 1 alpha, pro-interleukin-1-alpha, Hematopoietin-1, IL1A |
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| Gene, Accession # | Entrez: 16175; Uniprot: P01582 |
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| Catalog # | MA5-23736 |
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| Price | |
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| Order / More Info | IL-1 alpha Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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