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Antigenic Specificity | UBA2 |
Clone | OTI4A3 |
Host Species | Mouse |
Reactive Species | canine, human, nonhuman primate, rat |
Isotype | IgG2a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1:100, Immunofluorescence: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:500-1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | UBA2 Monoclonal Antibody (OTI4A3). Ubiquitin is covalently attached to target proteins by a multienzymatic system consisting of E1 (ubiquitin-activating), E2 (ubiquitin-conjugating), and E3 (ubiquitin-ligating) enzymes. NEDD8, a ubiquitin-like protein, is conjugated to proteins in a manner analogous to ubiquitinylation. beta-amyloid precursor protein-binding protein-1 (APPBP1) can bind to NEDD8 in rabbit reticulocyte lysates. However, since APPBP1 shows similarity to only the N-terminal domain of an E1 enzyme, it must interact with a protein showing similarity to the C-terminal region of E1s. By searching sequence databases, a cDNAs encoding UBA3 was identified as the human homolog of yeast Uba3. The predicted 442-amino acid UBA3 protein sh |
Immunogen | n/a |
Other Names | HRIHFB2115, ARX, SAE2; SUMO-1 activating enzyme subunit 2; SUMO-activating enzyme subunit 2; SUMO1 activating enzyme subunit 2; UBA2, ubiquitin-activating enzyme E1 homolog; anthracycline-associated resistance ARX; ubiquitin-like 1-activating enzyme E1B |
Gene, Accession # | Entrez: 10054, 308508, 476490, 705808; Uniprot: Q9UBT2 |
Catalog # | MA5-25437 |
Price | |
Order / More Info | UBA2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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