产品详情 |
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Antigenic Specificity | UBA3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µL |
Concentration | n/a |
Applications | Western Blot: 1:500-1:3000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | UBA3 Polyclonal Antibody. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have be |
Immunogen | n/a |
Other Names | UBE1C, hUBA3, NEDD8-activating enzyme E1 catalytic subunit, NEDD8-activating enzyme E1C, Nedd8-activating enzyme hUba3, UBA3, ubiquitin-activating enzyme E1 homolog, ubiquitin-activating enzyme 3, ubiquitin-activating enzyme E1C (UBA3 homolog, yeast), ubiquitin-activating en |
Gene, Accession # | Entrez: 9039; Uniprot: Q8TBC4 |
Catalog # | PA5-31225 |
Price | |
Order / More Info | UBA3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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