产品详情 |
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Antigenic Specificity | UBA3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine, canine, equine, human, mouse, porcine, rabbit, rat, zebrafish |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunocytochemistry: 1:500, Immunofluorescence: 1:500, Immunohistochemistry: 1:500, Western Blot: 0.2-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | UBA3 Polyclonal Antibody. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have be |
Immunogen | n/a |
Other Names | Ubiquitin-like modifier activating enzyme 3, DKFZp566J164, MGC22384, UBE1C, hUBA3 |
Gene, Accession # | Entrez: 100053395, 100153428, 100343309, 117553, 22200, 406776, 476560, 512647, 9039; Uniprot: Q7ZVX6, Q8C878, Q8TBC4, Q99MI7 |
Catalog # | PA5-43575 |
Price | |
Order / More Info | UBA3 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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