产品详情 |
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Antigenic Specificity | ISG15 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 400 µL |
Concentration | n/a |
Applications | Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ISG15 Polyclonal Antibody. ISG15 is secreted from monocytes in response to type I interferons and causes natural killer (NK)-cell proliferation and an augmentation of non-MCH (major histocompatibility complex)-restricted cytotoxicity. Synthesis is stimulated by IFN-alpha or IFN-beta or IFN-omega , but not IFN-gamma . ISG15 expression is also induced by overexpression of interferon regulatory factors that participate in transcriptional regulation of IFN genes, and by influenza B virus. ISG15 is secreted also by cell lines of monocyte, T-lymphocyte, B-lymphocyte, human fibroblasts, and epithelial origins. The induction of terminal differentiation in human melanoma cells is associated with alterations in ISG15 expression. Enhancement of NK cel |
Immunogen | n/a |
Other Names | Interferon-induced 17 kDa protein; Ubiquitin cross-reactive protein; hUCRP; Interferon-induced 15 kDa protein;G1P2, UCRP |
Gene, Accession # | Entrez: 9636; Uniprot: P05161 |
Catalog # | PA5-11269 |
Price | |
Order / More Info | ISG15 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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