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| Antigenic Specificity | Caspase Recruitment Domain Family, Member 8 (CARD8) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq] Synonyms: CARD8,CARDINAL,DACAR,DKFZp779L0366,Dakar,FLJ18119,FLJ18121,KIAA0955,MGC57162,NDPP,NDPP1,TUCAN , |
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| Immunogen | Recombinant protein of human CARD8 |
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| Other Names | CARD8|CARDINAL|DACAR|DAKAR|NDPP|NDPP1|TUCAN |
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| Gene, Accession # | Gene ID: 22900 |
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| Catalog # | ABIN1683432 |
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| Price | |
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| Order / More Info | Caspase Recruitment Domain Family, Member 8 (CARD8) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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