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| Product Name | JMJD Histone Demethylase Inhibitor III |
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| Description | Purity ~95% (HPLC). A substrate (methyl lysine) and cofactor (a-ketoglutarate) mimicking bivalent benzylamino-butylamino-N-hydroxybutenoic acid compound that acts as a selective in vitro inhibitor of Jumonji domain-containing histone demethylases (JHDMs; IC50=4.3, 3.4, 5.9, 10 and 43uM for JMJD2A, JMJD2C, JMJD2E, PHF8 and JMJD3, respectively) over LSD1, asparaginyl and prolyl hydroxylases, and histone deacetylases (IC50=54, 83, 31, 22, 620, 680 and >800uM for PHD1, PHD2, PHD3, FIH, LSD1 and HDACs, respectively). The cellular active JHDM Inhibitor, Methylstat is also available. Formula: C27H29N3O6 Solubility: DMSO Molecular Weight: 491.5 |
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| Size | 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | JMJD Histone Demethylase Inhibitor III ((E)-4-(Hydroxy(4-(4-((naphthalen-1-ylcarbamoyloxy)methyl)benzylamino)butyl)amino)-4-oxobut-2-enoic Acid) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217482 |
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| Order / More Info | JMJD Histone Demethylase Inhibitor III from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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