产品详情 |
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Antigenic Specificity | EBP50 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry: 2 µg/mL, Immunofluorescence: 2 µg/mL, Immunohistochemistry (Paraffin): 10 µg/mL, Immunoprecipitation: Assay dependent, Western Blot: 1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | EBP50 Polyclonal Antibody. EBP50 [ERM (ezrin-radixin-moesin) binding phosphoprotein of 50 kDa] is a PDZ containing protein that is involved in the linkage of integral membrane proteins to the cytoskeleton. EBP50 contains two tandem PDZ domains followed by a carboxy-terminal sequence that binds to members of the ERM family of membrane-cytoskeleton adaptors. The PDZ domains within EBP50 bind to the carboxy termini of such target proteins as beta2 adrenergic receptor, platelet-derived growth factor receptor (PDGFR), and the cystic fibrosis conductance regulator (CFTR). The PDZ domains are also believed to be involved in the oligomerization of EBP50 to form multiprotein complexes which helps to facilitate the formation of functional signalling |
Immunogen | n/a |
Other Names | Ezrin-Radixin-Moesin Binding Phosphoprotein 50, NHERF, Na(+)/H(+) exchange regulatory cofactor NHE-RF, Regulatory cofactor of Na(+)/H(+) exchanger, So |
Gene, Accession # | Entrez: 26941, 9368; Uniprot: O14745, P70441 |
Catalog # | PA1-090 |
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Order / More Info | EBP50 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 12920119, 14625387, 15805108, 17504921, 17593079, 17705417, 19805521, 19912366, 20562104, 20940332, 21444686, 21496870, 21707710, 21804599, 22439624, 22440733, 22766563, 23109343, 23868408, 23991686, 24116027, 24201803, 25744438, 26126066, 26312763, 27566107, 27765918, 27823775, 29152120 |
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