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Antigenic Specificity | Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (N-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 50 µg |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CHRNA4 is a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. |
Immunogen | CHRNA4 antibody was raised using the N terminal of CHRNA4 corresponding to a region with amino acids AEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTT |
Other Names | NACHRA4|BFNC|EBN|EBN1|NACHR|NACRA4|NARAC|Acra-4|Acra4|ENFL1 |
Gene, Accession # | Gene ID: 1137,11438,25590 |
Catalog # | ABIN633758 |
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Order / More Info | Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4) (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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