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| Product Name | PACAP (6-38), human, ovine, rat |
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| Description | Purity >95%. PACAP (6-38) is a potent antagonist of PACAP 38. PACAP (6-38) is much more potent and selective than PACAP (6-27) in the inhibition of PACAP-27-stimulated pituitary adenylate cyclase. Ki values for the inhibition of the enzyme were 7nM and 150 nM;respectively. PACAP (6-38) caused a small but significant (approximately 20%) inhibition of the NANC relaxation due to electrical field stimulation (1 Hz or 10 Hz for 20 s). At these frequencies PACAP (6-38) caused no inhibition of the NANC relaxation in the presence of the P2 purinoceptor antagonist pyridoxal-phosphate-6-azophenyl-2';4'-disulphonic acid (or PPADS) plus the NO-synthase blocker NG-nitro-L-arginine;in preparations pretreated with L-NOARG alone;PACAP (6-38) retained its inhibitory effect. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | LS-H4840 |
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| Order / More Info | PACAP (6-38), human, ovine, rat from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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