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| Product Name | Proteinase 3, Human Neutrophil |
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| Description | Purity ~95% (SDS-PAGE). Proteinase 3 is one of the serine proteinases localized in azurophil granules of polymorphonuclear leukocytes. It has been identified as the autoantigen of Wegener granulomatosis, a systemic vasculitis complicated by melomonocyte proliferation. It exhibits proteolytic activity towards a range of substrates. It is physiologically inhibited by alpha1-antitrypsin. The protein has been described as having antibiotic and growth-promoting properties and causing emphysema when administered by tracheal insufflation. Source: Human Neutrophils Molecular Weight: ~29kD |
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| Size | 25ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Proteinase 3, Human Neutrophil (PR3, AGP7, C-ANCA antigen, Leukocyte proteinase 3, Neutrophil proteinase 4, P29, Wegener autoantigen) |
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| Gene, Accession, CAS # | AGP7, Gene ID: 5657, SwissProt: P24158 |
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| Catalog # | P1212 |
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| Order / More Info | Proteinase 3, Human Neutrophil from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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