| 产品详情 |
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| Product Name | Brefeldin A |
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| Description | Purity >98%. Brefeldin A (BFA) is a natural fungal metabolite which has been used extensively to study intracellular transport by vesicles or endosomes. Early studies demonstrated that BFA reversibly interferes with protein trafficking and secretion mediated by the Golgi apparatus and endoplasmic reticulum. BFA directly and reversibly inhibits Sec7 domain-containing guanine-exchange factors which are necessary for ADP-ribosylation factor activation associated with vesicular transport (IC50 = ~10 µM). BFA is used to study endosomal trafficking and function in cells of plants as well as those of fungi, invertebrates, and vertebrates. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (1R,2E,6S,10E,11aS,13S,14aR)-1,6,7,8,9,11a,12,13,14,14a-decahydro-1,13-dihydroxy-6-methyl-4H-cyclopent[f]oxacyclotridecin-4-one, Ascotoxin, Cyanein, Decumbin, Synergisidin, BFA, Nectrolide, NSC 107456, NSC 244390, NSC 56310, NSC 89671 |
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| Gene, Accession, CAS # | CAS: 20350-15-6 |
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| Catalog # | LS-H6898 |
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| Order / More Info | Brefeldin A from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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