| 产品详情 |
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| Antigenic Specificity | TSPAN12 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Alexa Fluor® 680 conjugate |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TSPAN12 Polyclonal Antibody, Alexa Fluor® 680 Conjugated. • Target Background: Regulator of cell surface receptor signal transduction. Plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction. Acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. Suprisingly, it only activate the norrin (NDP)-dependent activation of FZD4, while it does not activate the Wnt-dependent activation |
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| Immunogen | KLH conjugated synthetic peptide derived from human TSPAN12. Immunogen Range: 34-50/305 |
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| Other Names | EVR5; NET2; NET-2; TM4SF12; Tetraspanin-12; Tspan-12; Tetraspan NET-2; Transmembrane 4 superfamily member 12; TSPAN12; UNQ774/PRO1568 |
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| Gene, Accession # | Gene ID: 23554, SwissProt: O95859 |
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| Catalog # | bs-10425R-A680 |
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| Price | |
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| Order / More Info | TSPAN12 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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| 产品资料 |
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