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Product Name | NEDD8 Conjugation Reaction Buffer (10X) |
Description | NEDD8 (Neural precursor cell-expressed developmentally down-regulated gene 8, also known as Rub1) is a 6-8 kDa member of the ubiquitin family of proteins. It is expressed in striated muscle, and via its C-terminal Gly, forms covalent bonds with cullin family proteins. This conjugation generates ubiquitin ligase activity that regulates cell cycle proteins. Human pro-NEDD8 is 81 amino acids (aa) in length. It contains one ubiquitin-like domain (aa 1-65), and a 4-5 aa C-terminal propeptide that is cleaved to expose a C-terminal Gly residue that is used to generate a Gly-Lys intermolecular bond. Mature human NEDD8 shows 100% aa identity to NEDD8 from both mouse and canine. |
Size | 5 mL |
Concentration | n/a |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | n/a |
Catalog # | ABIN2745414 |
Price | |
Order / More Info | NEDD8 Conjugation Reaction Buffer (10X) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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