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Antigenic Specificity | Complement C3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, bovine |
Isotype | n/a |
Format | Protein A purified |
Size | 100ul |
Concentration | 1ug/ul |
Applications | IHC-P, IHC-F, IF(IHC-P), IF(IHC-F) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Complement C3 Polyclonal Antibody. • Target Background: C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. In chronic inflammation, acts as a chemoattractant for neutrophils (By similarity |
Immunogen | KLH conjugated synthetic peptide derived from human Complement C3 alpha chain. Immunogen Range: 1611-1631/1663 |
Other Names | ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p; Complement C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1; C3 |
Gene, Accession # | Gene ID: 718, SwissProt: P01024 |
Catalog # | bs-2934R |
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Order / More Info | Complement C3 Antibody from BIOSS ANTIBODIES |
Product Specific References | Trang, N. T., et al. (2014) J Comp Pathol. PubMed: 25005673 // Zhuang, Haoyang, et al. (2016) Arthritis Rheumatol. PubMed: 27274010 // Rogi?ska, Dorota, et al. (2017) Oxid Med Cell Longev. // Rogi?ska et al. (2017) Oxid.Med.Cell.Longe. 2017:5306790. PubMed: 28928904 // Liao et al. (2015) PLoS.One. 10:e0132724. PubMed: 26161538 |
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