| 产品详情 |
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| Product Name | N-Dodecanoyl-DL-homoserine lactone |
| Description | Purity >97% by GC. N-Dodecanoyl-DL-homoserine lactone (C12-HSL) is a small diffusible signalling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism in bacteria. In addition to regulating bacterial functions, C12-HSL activates NF-kappaB in RAW 264.7 macrophages, increasing the expression of TNF-alpha, interleukin-1beta (IL-1beta) and IL-8, while other lactones do not. In addition, C12-HSL alters cell cycling and metabolism of human keratinocyte (HaCaT) cells. It also was shown to induce cell death by apoptosis. |
| Size | n/a |
| Concentration | n/a |
| Applications | n/a |
| Other Names | C12-HSL, N-(2-Oxotetrahydro-3-furanyl)dodecanamide, N-Lauroyl-DL-homoserine lactone |
| Gene, Accession, CAS # | CAS: 18627-38-8 |
| Catalog # | LS-H1092 |
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| Order / More Info | N-Dodecanoyl-DL-homoserine lactone from LIFESPAN BIOSCIENCES INC. |
| Product Specific References | n/a |
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