产品名称 N-Dodecanoyl-DL-homoserine lactone from LIFESPAN BIOSCIENCES INC.
产品货号 LS-H1092
产品价格 现货询价,电话:010-67529703
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产品品牌 LIFESPAN BIOSCIENCES INC.
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Product NameN-Dodecanoyl-DL-homoserine lactone
DescriptionPurity >97% by GC. N-Dodecanoyl-DL-homoserine lactone (C12-HSL) is a small diffusible signalling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism in bacteria. In addition to regulating bacterial functions, C12-HSL activates NF-kappaB in RAW 264.7 macrophages, increasing the expression of TNF-alpha, interleukin-1beta (IL-1beta) and IL-8, while other lactones do not. In addition, C12-HSL alters cell cycling and metabolism of human keratinocyte (HaCaT) cells. It also was shown to induce cell death by apoptosis.
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Other NamesC12-HSL, N-(2-Oxotetrahydro-3-furanyl)dodecanamide, N-Lauroyl-DL-homoserine lactone
Gene, Accession, CAS #CAS: 18627-38-8
Catalog #LS-H1092
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Order / More InfoN-Dodecanoyl-DL-homoserine lactone from LIFESPAN BIOSCIENCES INC.
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