| 产品详情 |
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| Product Name | N-Dodecanoyl-L-homoserine lactone |
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| Description | Purity >98% by NMR. N-Dodecanoyl-L-homoserine lactone (C12-HSL) is a small diffusible signalling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism in bacteria. In addition to regulating bacterial functions, C12-HSL activates NF-kappaB in RAW 264.7 macrophages, increasing the expression of TNF-alpha, interleukin-1beta (IL-1beta) and IL-8, while other lactones do not. In addition, C12-HSL alters cell cycling and metabolism of human keratinocyte (HaCaT) cells. It is important to note that C12-HSL is distinct from N-3-oxo-dodecanoyl-L-homoserine lactone, which is produced at different times in biofilm development and has different cellular effects. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | C12-HSL, dDHL, N-[(3S)-Tetrahydro-2-oxo-3-furanyl]-dodecanamide |
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| Gene, Accession, CAS # | CAS: 137173-46-7 |
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| Catalog # | LS-H1094 |
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| Order / More Info | N-Dodecanoyl-L-homoserine lactone from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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