产品详情 |
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Antigenic Specificity | CD5 |
Clone | 4C7 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | purified |
Size | 500 µL |
Concentration | n/a |
Applications | Flow Cytometry: 1:2, Immunohistochemistry (Paraffin): 1:20-1:40, Western Blot: 1:10-1:200 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD5 Monoclonal Antibody (4C7). CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome. |
Immunogen | n/a |
Other Names | CD5 antigen p56-62, T-cell surface glycoprotein CD5, lymphocyte antigen T1/Leu-1 |
Gene, Accession # | Entrez: 921; Uniprot: P06127 |
Catalog # | MA5-13308 |
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Order / More Info | CD5 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | PubMed: 11979093, 12431245, 12883242, 15089768, 15842046, 17038534, 17057651, 17090191, 17102815, 17669469, 18091393, 18477041, 19372083, 20002767, 20441508, 20551275, 21044186, 21502423, 21995633, 22257663, 22640627, 23557559, 27199251, 27479326 |
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