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Product Name | Human VEGI protein |
Description | TNFSF15 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of TNFSF15 is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. TNFSF15 is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this transcript has not been determined. MW: 21.8 kDa. Purity > 95.0% |
Size | 10 ug |
Concentration | n/a |
Applications | HPLC, SDS-PAGE |
Other Names | Tumor necrosis factor ligand superfamily member 15 protein, TNFSF-15 protein, TNFSF15 protein, TNF ligand-related molecule 1 protein, VEGI protein, TL-1 protein, TL1 protein, TL1A protein, VEGI192A protein, VEGI-192 protein, MGC129934 protein, MGC129935 protein |
Gene, Accession, CAS # | n/a |
Catalog # | orb180577 |
Price | |
Order / More Info | Human VEGI protein from BIORBYT LTD. |
Product Specific References | n/a |
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