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Product Name | Interleukin 1, beta (IL1B) (AA 117-269) (Active) protein |
Description | Interleukin-1 beta (rhIL-1β) is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1 beta is a secreted cytokine, IL-1 alpha is predominantly a cell-associated cytokine. Recombinant human Interleukin-1 beta (rhIL-1β) produced in E. coli is a single non-glycosylated polypeptide chain containing 153 amino acids. A fully biologically active molecule, rhIL-1β has a molecular mass of 17.3kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques. Synonyms: Catabolin, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF), IL1F2, IL-1 beta. |
Size | 1 mg |
Concentration | n/a |
Applications | n/a |
Other Names | il1-b|zgc:111873|IL-1beta|Il-1b|IL1B|IL-1|IL1-BETA|IL1F2|IL-1BETA|IL1beta|IL-1B |
Gene, Accession, CAS # | Gene ID: 3553 |
Catalog # | ABIN2018037 |
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Order / More Info | Interleukin 1, beta (IL1B) (AA 117-269) (Active) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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