产品详情 |
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Antigenic Specificity | ERCC8/CSA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Alexa Fluor® 750 conjugate |
Size | 100ul |
Concentration | 1ug/ul |
Applications | IF(IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ERCC8/CSA Polyclonal Antibody, Alexa Fluor® 750 Conjugated. • Target Background: Substrate-recognition component of the CSA complex, a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex, involved in transcription-coupled nucleotide excision repair. The CSA complex (DCX(ERCC8) complex) promotes the ubiquitination and subsequent proteasomal degradation of ERCC6 in a UV-dependent manner; ERCC6 degradation is essential for the recovery of RNA synthesis after transcription-coupled repair. It is required for the recruitment of XAB2, HMGN1 and TCEA1/TFIIS to a transcription- |
Immunogen | KLH conjugated synthetic peptide derived from human ERCC8/CSA. Immunogen Range: 180-230/396 |
Other Names | CSA; CKN1; UVSS2; DNA excision repair protein ERCC-8; Cockayne syndrome WD repeat protein CSA; ERCC8 |
Gene, Accession # | Gene ID: 1161, SwissProt: Q13216 |
Catalog # | bs-13095R-A750 |
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Order / More Info | ERCC8/CSA Antibody from BIOSS ANTIBODIES |
Product Specific References | n/a |
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