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| Product Name | GW 6471 |
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| Description | Purity >98%. The peroxisome proliferator-activated receptor Alpha (PPARAlpha) is a nuclear receptor that regulates the expression of genes involved in fatty acid metabolism, lipoprotein synthesis and metabolism, and inflammation. GW 6471 is an antagonist of PPARAlpha (IC50 = 240 nM). It drives the displacement of coactivators from PPARAlpha and promotes the recruitment of co-repressor proteins like nuclear co-repressor. GW 6471 is used in cell-free, cell lysate, and whole cell systems to examine the impact of PPARAlpha antagonism. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[(2S)-2-[[(1Z)-1-methyl-3-oxo-3-[4-(trifluoromethyl)phenyl]-1-propen-1-yl]amino]-3-[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]phenyl]propyl]-propanamide |
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| Gene, Accession, CAS # | CAS: 880635-03-0 |
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| Catalog # | LS-H8056 |
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| Order / More Info | GW 6471 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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