| 产品详情 |
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| Antigenic Specificity | Factor XII Heavy chain |
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| Clone | B7C9 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 250 ug |
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| Concentration | n/a |
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| Applications | ELISA: 1-10 µg/mL, Western Blot: 1-10 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Factor XII Heavy chain Monoclonal Antibody (B7C9). This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves facto |
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| Immunogen | n/a |
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| Other Names | HAE3, HAEX, HAF |
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| Gene, Accession # | Entrez: 2161; Uniprot: P00748 |
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| Catalog # | MA1-10828 |
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| Price | |
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| Order / More Info | Factor XII Heavy chain Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 20128864 |
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