| 产品详情 |
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| Antigenic Specificity | CD247 (CD3 zeta) |
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| Clone | 6B10.2 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry: 0.25 µg/test |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD247 (CD3 zeta) Monoclonal Antibody (6B10.2), PE, eBioscience™. CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the |
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| Immunogen | n/a |
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| Other Names | T3Z, CD3H, CD3Q, TCRZ, CD3-ZETA |
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| Gene, Accession # | Entrez: 919; Uniprot: P20963 |
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| Catalog # | 12-2479-82 |
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| Price | |
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| Order / More Info | CD247 (CD3 zeta) Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 27637084 |
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