产品详情 |
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Antigenic Specificity | Separase |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunofluorescence: 1.0 µg/mL, Western Blot: 1.0 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Separase Polyclonal Antibody. Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 or STAG2 in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 by ESPL1, or separase, which initiates the final separation of sister chromatids . |
Immunogen | n/a |
Other Names | ESP1, FLJ46492, KIAA0165, caspase-like protein ESPL1; extra spindle poles like 1; extra spindle poles-like 1 protein; separin |
Gene, Accession # | Entrez: 105988, 9700; Uniprot: P60330, Q14674 |
Catalog # | PA5-19419 |
Price | |
Order / More Info | Separase Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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