产品详情 |
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Antigenic Specificity | TL1A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA: Assay Dependent, Western Blot: Assay Dependent |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TL1A Polyclonal Antibody. Members in the TNF and its receptor superfamilies regulate immune responses and induce apoptosis. DR3 (also termed Wsl-1, Apo-3, TRAMP, and LARD) is preferentially expressed by T lymphocytes and upregulated during T cell activation. The ligand for DR3 was recently identified and designated TL1A. TL1A also binds decoy receptor DcR3/TR6, which is expressed in several lung and colon carcinomas and in some normal tissues. TL1A induces apoptosis and NF-kappa-B activation in DR3 expressing cells, which is antagonized by DcR3. TL1A is upregulated by proinflammatory cytokines TNF and IL-1. TL1A is a longer variant of TL1 (also called VEGI). |
Immunogen | n/a |
Other Names | TL1, TL1A, VEGI, VEGI192A, TNF ligand-related molecule 1, TNF superfamily ligand TL1A, tumor necrosis factor ligand superfamily member 15, vascular endothelial cell growth inhibitor, vascular endothelial growth inhibitor-192A |
Gene, Accession # | Entrez: 9966; Uniprot: O95150 |
Catalog # | 34-3900 |
Price | |
Order / More Info | TL1A Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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