| 产品详情 |
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| Antigenic Specificity | TL1A |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blot: 0.5-2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TL1A Polyclonal Antibody. Members in the TNF and its receptor superfamilies regulate immune responses and induce apoptosis. DR3 (also termed Wsl-1, Apo-3, TRAMP, and LARD) is preferentially expressed by T lymphocytes and upregulated during T cell activation. The ligand for DR3 was recently identified and designated TL1A. TL1A also binds decoy receptor DcR3/TR6, which is expressed in several lung and colon carcinomas and in some normal tissues. TL1A induces apoptosis and NF-kappa-B activation in DR3 expressing cells, which is antagonized by DcR3. TL1A is upregulated by proinflammatory cytokines TNF and IL-1. TL1A is a longer variant of TL1 (also called VEGI). |
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| Immunogen | n/a |
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| Other Names | TL1, TL1A, VEGI, VEGI192A; TNF ligand-related molecule 1; TNF superfamily ligand TL1A; tumor necrosis factor ligand superfamily member 15; vascular endothelial cell growth inhibitor; vascular endothelial growth inhibitor-192A |
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| Gene, Accession # | Entrez: 252878, 326623, 9966; Uniprot: O95150, Q5UBV8, Q8K3Y7 |
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| Catalog # | PA5-20015 |
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| Price | |
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| Order / More Info | TL1A Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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