产品详情 |
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Antigenic Specificity | TL1A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot: 0.5-1 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TL1A Polyclonal Antibody. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. An additional isoform encoded by an alternatively spliced transcript variant has been reported but the sequence of this tr |
Immunogen | n/a |
Other Names | MGC129934, MGC129935, TL1, TL1A, VEGI, VEGI192A |
Gene, Accession # | Entrez: 252878, 326623, 9966; Uniprot: O95150, Q5UBV8, Q8K3Y7 |
Catalog # | PA1-32468 |
Price | |
Order / More Info | TL1A Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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