| 产品详情 |
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| Product Name | O4 |
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| Description | Purity >98% by HPLC. Orcein-related small molecule that accelerates ABeta fibrillogenesis. It directly binds to hydrophobic amino acid residues in ABeta peptides and stabilizes the self-assembly of seeding-competent, Beta-sheet-rich protofibrils and fibrils. The mediated acceleration of amyloid fibril formation efficiently decreases the concentration of small, toxic ABeta oligomers in complex, heterogeneous aggregation reactions. In addition, it suppresses inhibition of long-term potentiation by ABeta oligomers in hippocampal brain slices. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 7-Amino-2,8-bis(2,4-dihydroxyphenyl)-3H-phenoxazin-3-one |
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| Gene, Accession, CAS # | CAS: 33869-21-5 |
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| Catalog # | LS-H11149 |
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| Price | |
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| Order / More Info | O4 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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