| 产品详情 |
| Edit |   |
|---|
| Product Name | Fumarate Hydratase (FH) (AA 44-510) protein |
|---|
| Description | Fumarase is an enzymatic factor of Krebs cycle, which catalyzes the formation of L-malate from fumarate. Fumarase exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is aimed to the mitochondrion, where the removal of the extension results in the same form as in the cytoplasm. Fumarase is similar to a number of thermostable Class-2 fumarases and functions as a homotetramer. Mutations in the Fumarase gene causes fumarase deficiency and leads to progressive encephalopathy, cerebral atrophy and developmental delay. Fumarase enzyme is also thought to act as a tumor suppressor. Leydig cell tumors are caused by Fumarase mutations and represents one of the first reports of germline mutations in any type of adult testicular tumor Synonyms: MCL, LRCC, HLRCC, MCUL1, FH, Fumarate hydratase, Fumarase |
|---|
| Size | 1 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | FH|DDBDRAFT_0205237|DDBDRAFT_0231397|DDBDRAFT_0231400|DDB_0205237|DDB_0231397|DDB_0231400|HLRCC|LRCC|MCL|MCUL1|Fh1|im:7152785|ns:zf-e152|zf-e152|zgc:66253|zgc:77498|Fh|Fh-1 |
|---|
| Gene, Accession, CAS # | Gene ID: 2271 |
|---|
| Catalog # | ABIN805647 |
|---|
| Price | |
|---|
| Order / More Info | Fumarate Hydratase (FH) (AA 44-510) protein from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|