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| Product Name | Recombinant Human Protein FAM19A2 protein (FAM19A2) (Active) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 43.2kDa. Heterodimer: 24-155aa & 31-163aa. C-terminal 6xHis-tagged. Homo sapiens (Human). The IL-17 family include IL-17A, IL-17B, IL-17C, IL-17D, IL-17E (also called IL-25), and IL-17F. The family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. All members of the IL-17 family have a similar protein structure, with four highly conserved cysteine residues critical to their 3-dimensional shape, yet they have no sequence similarity to any other known cytokines. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | IL-17A/F Heterodimer; IL-17A&IL-17F Heterodimer |
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| Gene, Accession, CAS # | IL17A & IL17F, UniProt: Q16552 & Q96PD4 |
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| Catalog # | RPC26916 |
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| Order / More Info | Recombinant Human Protein FAM19A2 protein (FAM19A2) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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