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| Product Name | Methicillin Sodium, USP |
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| Description | Methicillin sodium is a narrow spectrum β-lactam antibiotic related to Penicillin. β-lactams interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP's are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to β-lactams is commonly due to cells containing plasmid encoded β-lactamases. Methicillin is mostly resistant to β-lactamases. Methicillin targets primarily the cell wall of Gram positive organisms especially Staphylococcus aureus. Water (Karl Fisher): ≤10% |
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| Size | 50mg, 250mg, 500mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Sodium (2,6-dimethoxyphenyl)penicillin; (2S,5R,6R)-6-[(2,6-Dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Sodium Salt; Meticillin; Staphcillin |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 16110 |
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| Price | |
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| Order / More Info | Methicillin Sodium, USP from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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