产品详情 |
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Antigenic Specificity | OAT (aa 33-439) |
Clone | PAT23A2AT- |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 100 µg |
Concentration | n/a |
Applications | ELISA,Western Blotting (WB),Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ornithine aminotransferase is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Ornithine aminotransferase (OAT) is a 49 kDa nucleus-encoded protein imported into mitochondria to give the mature 49 kDa OAT polypeptide. It is found in humans, animals, insects, plants and microorganisms. The OAT has a sex-differential expression in the mouse kidney. OAT plays central physiological roles in amino acid metabolism. OAT shows a large structural and mechanistic similarity to other enzymes from the subgroup III of aminotransferases that transfer an amino group from a carbon atom which doesn't carry a carboxyl function. OAT is vital for nitrogen recycling from arginine but not for the stress-induced proline accumulation. OAT enzyme deficiency causes the autosomal recessive eye disease Gyrate Atrophy |
Immunogen | Anti-human OAT mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with recombinant human OAT AA 33-439 |
Other Names | Ornithine aminotransferase mitochondrial, Ornithine delta-aminotransferase, Ornithine-oxo-acid aminotransferase, OAT, OKT, GACR, HOGA, OATASE, DKFZp781A11155 |
Gene, Accession # | n/a |
Catalog # | ABIN808027 |
Price | |
Order / More Info | OAT (aa 33-439) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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