| 产品详情 |
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| Product Name | RG7388 |
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| Description | Purity >99% by HPLC. RG7388 is highly a potent and selective inhibitor of p53-MDM2 interaction. RG7388 blocks p53-MDM2 binding and effectively activates the p53 pathway, leading to cell cycle arrest and/or apoptosis in cell lines expressing wild-type p53 and tumor growth inhibition or regression of osteosarcoma xenografts in nude mice. A potent and selective inhibitor of p53-MDM2 interaction. (Biochemical) |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 4-[[(2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carbonyl]amino]-3-methoxybenzoic acid |
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| Gene, Accession, CAS # | CAS: 1229705-06-9 |
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| Catalog # | LS-H3145 |
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| Order / More Info | RG7388 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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