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Antigenic Specificity | SGPL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 400 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:1000, Western Blot: 1:1000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SGPL1 Polyclonal Antibody. Sphingosine-1-phosphate lyase cleaves phosphorylated sphingoid bases, such as sphingosine-1 phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. The catalytic activity of sphingosine 1- phosphate lyase converts sphingosine 1-phosphate to phosphoethanolamine and palmitaldehyde using Pyridoxal phosphate as a co-factor. Sphingosine 1-phosphate lyase is a type III membrane protein found in the endoplasmic reticulum. Sphingosine 1-phosphate lyase is found primarily in the liver and kidney. Sphingosine 1-phosphate lyase belongs to the group II decarboxylase family. |
Immunogen | n/a |
Other Names | Sphingosine-1-phosphate lyase 1; S1PL; SP-lyase 1; SPL 1; hSPL; Sphingosine-1-phosphate aldolase; SGPL1; KIAA1252 |
Gene, Accession # | Entrez: 8879; Uniprot: O95470 |
Catalog # | PA5-71745 |
Price | |
Order / More Info | SGPL1 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |