产品详情 |
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Antigenic Specificity | TMEM43 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 100 µl |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin): 1:50-1:200, Western Blot: 1:500-1:2000 |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TMEM43 Polyclonal Antibody. This gene belongs to the TMEM43 family. Defects in this gene are the cause of familial arrhythmogenic right ventricular dysplasia type 5 (ARVD5), also known as arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5). Arrhythmogenic right ventricular dysplasia is an inherited disorder, often involving both ventricles, and is characterized by ventricular tachycardia, heart failure, sudden cardiac death, and fibrofatty replacement of cardiomyocytes. This gene contains a response element for PPAR gamma (an adipogenic transcription factor), which may explain the fibrofatty replacement of the myocardium, a characteristic pathological finding in ARVC. |
Immunogen | n/a |
Other Names | LUMA; ARVC5; ARVD5; EDMD7; |
Gene, Accession # | Entrez: 74122, 79188; Uniprot: Q9BTV4, Q9DBS1 |
Catalog # | PA5-76407 |
Price | |
Order / More Info | TMEM43 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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