| 产品详情 |
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| Product Name | 5-Fluorouracil |
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| Description | Purity 98%. 5-Fluorouracil is a clinically useful anticancer agent that acts via irreversible inhibition of thymidylate synthase. The active metabolites of 5-Fluorouracil are 5-Fluorodeoxyuridylate (5-FdUMP), 5-Fluorodeoxyuridine triphosphate (5-FdUTP) and 5-Fluorouridine triphosphate (5-FUTP). The primary cytotoxic effect of 5-Fluorouracil is believed to be inhibition of thymidylate synthase by 5-FdUMP. Secondary effects include incorporation of 5-FdUTP into DNA resulting in DNA strand breaks and incorporation of 5-FUTP into RNA causing abnormal RNA processing. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 5-Fluoro-1H,3H-pyrimidine-2,4-dione |
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| Gene, Accession, CAS # | CAS: 51-21-8 |
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| Catalog # | LS-H14570 |
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| Order / More Info | 5-Fluorouracil from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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